Life-threatening tracheal perforation secondary to descending necrotizing mediastinitis

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Abstract

Survival from destruction of the mediastinal structures secondary to descending necrotizing mediastinitis (DNM) is very rare. We present a successfully treated case of tracheal perforation secondary to DNM. A 34-year-old man with a history of type 1 diabetes mellitus, diagnosed as pharyngeal abscess and subsequent DNM affecting the anterior mediastinum and paratracheal space, was referred to our institute. The patient underwent cervico-mediastinal drainage for DNM. Nine days after the drainage operation, the membranous portion of the trachea perforated, resulting in life-threatening ventilation failure. The patient underwent closure of the fistula with the pedicled intercostal muscle flap under posterolateral thoracotomy with veno-venous extracorporeal membranous oxygenation support. Before complete recovery, open window thoracostomy was required to control residual air leak.

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Murakawa, T., Yoshida, Y., Fukami, T., & Nakajima, J. (2010). Life-threatening tracheal perforation secondary to descending necrotizing mediastinitis. Interactive Cardiovascular and Thoracic Surgery, 10(3), 454–456. https://doi.org/10.1510/icvts.2009.225912

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