Thiadiazine Derivatives as Antiprotozoal New Drugs

  • Bermello J
  • Piñeiro R
  • Fidalgo L
  • et al.
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Abstract

The 3,5-disubstituted tetrahydro-2H-1,3,5-thiadiazine-2-thione scaffold have found many applications in recent years. This review is aimed at highlighting the most important aspects about these compounds: synthesis, spectroscopic characterization and antiprotozoan activities. How the chemical nature of N-substituents influences the overall activity / cytotoxicity profile will also be discussed.

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Bermello, J. C., Piñeiro, R. P., Fidalgo, L. M., Cabrera, H. R., & Navarro, M. S. (2011). Thiadiazine Derivatives as Antiprotozoal New Drugs. The Open Medicinal Chemistry Journal, 05(1), 51–60. https://doi.org/10.2174/1874104501105010051

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