Alterações tomográficas cerebrais em crianças com lesões oculares por toxoplasmose congênita

Abstract

1. Professor do Depto. de Oftalmologia e Otorrinolaringologia da Faculdade de Medicina da Universidade Federal do Rio Grande do Sul (UFRGS). Chefe do Setor de Uveítes do Serviço de Oftalmologia do Hospital de Clínicas de Porto Alegre (HCPA). 2. Residente do Serviço de Oftalmologia do HCPA. 3. Acadêmica da Faculdade de Medicina da UFRGS. Artigo submetido em 29.01.01, aceito em 16.05.01. Abstract Objective: to evaluate the frequency and the types of cerebral CT scan alterations in patients with ocular lesions caused by con-genital toxoplasmosis. Methods: the patients should fit one of the following criteria: reagent IgM serology for toxoplasmosis at birth and mother with positive serology for toxoplasmosis; age less than ten years, with bilateral funduscopic lesions compatible with toxoplasmic retin-ochoroiditis; or reagent IgG serology for toxoplasmosis and mother with positive serology for toxoplasmosis. All patients were submit-ted to noncontrast cerebral CT scan. Results: twenty-two patients participated in this study (44 eyes). Thirteen eyes presented macular lesions (29.5%), eight had peripheral lesions (18.2%) and 22 eyes had concomitant macular and peripheral lesions (50%). Seventeen patients presented radiological alterations (77.3%). Among these, sixteen patients (94.1%) pre-sented brain calcifications, two patients (11.7%) presented ventricu-lar dilation, two patients (11.7%) had hydrocephalus, one had hydranencephaly (5.9%), one presented porencephalic cyst (cere-bral hemiatrophy) (5.9%), one had arachnoid cyst (5.9%) and one had mild dilation of ventricles and subarachnoid cistern (5.9%). Conclusions: patients diagnosed with congenital toxoplasmo-sis and ocular lesions should be investigated for concomitant neuroradiologic alterations.