The biological activity of aqueous and methanolic extracts of Juglans Regia on yeasts and pathologic bacteria

Abstract

In this study Juglans regia extracts showed activities against Malassezia furfur yeast, Methanolic extract exhibits more activity than aqueous extract. The Minimum Inhibition Concentrated rate (MIC) for Malassezia furfur methanolic extract was 75μg/ml. The extracts also examined on Candida albicans opportunistic yeast in the mouth) and found to be more active than M. furfur were MIC 50 μg/ml. The biological activity of aqueous and methanolic extracts were also examined against six pathogenic bacteria isolated from patients suffering from different diseases from several hospitals in Basrah, including Staphylococcus aureus, Escherichia coli, Salmonella typhi, Proteus mirabilis, pseudomonas aeruginosa and Vibrio parahaemolyticus. The Methanolic extract showed an effective effect in inhibiting all bacterial species compared with the aqueous extract. This study provides the possibility of using a natural plant such as Juglans regia antimicrobial agent for many pathogenic yeasts and bacteria.