Sub-mm resolution tomographic imaging in turbid media by an ultra-high density multichannel approach

Abstract

We demonstrate an ultra-high-density source-detector (SD) diffuse optical tomography system scalable to thousands of combinatorial SD pairs per cm 3 of total voxel volume. We demonstrate the imaging of dynamic targets (including phantom arteries) with 100 um resolution at over 10 Hz frame rate within turbid media (> 60 MFP). Further, as a step toward a wearable mobile imager, we introduce monolithic mm-size dense semiconductor laser array chips as sources for potential unobtrusive epidermal tomographic use.