Earliest identification of new delhi metallo-β-lactamase 1 (NDM-1) in acinetobacter pittii in Brazil

Abstract

We report the occurrence in Brazil of the blaNDM-1 gene in Acinetobacter pittii, prior to the previously described first reports regarding the species Providencia rettgeri and Enterobacter hormaechei. Clinical isolates were investigated by polymerase chain reaction followed by bidirectional sequencing, and species was confirmed by 16S rDNA sequencing and matrix-assisted laser desorption-ionization time-of-flight spectrometry. A. pittii carrying blaNDM-1 was confirmed in a patient with no national or international travel history, or transfer from another hospital. The findings warn of the possibility of silent spread of blaNDM-1 to the community.