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Deep sequencing of varicella-zoster virus in aqueous humor from a patient with acute retinal necrosis presenting with acute glaucoma

Open Forum Infectious Diseases (2020) 7(6)
DOI: 10.1093/OFID/OFAA198
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Abstract

We report a case of acute retinal necrosis presenting with acute glaucoma preceding inflammatory signs by several days. Highthroughput sequencing on aqueous humor revealed a low-level diversity in the viral genome comparable to diversity seen in cutaneous vesicles in contrast to high diversity in encephalitis.

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Von Hofsten, J., Ringlander, J., Norberg, P., Zetterberg, M., Andersson, M., Lindh, M., & Bergström, T. (2020). Deep sequencing of varicella-zoster virus in aqueous humor from a patient with acute retinal necrosis presenting with acute glaucoma. Open Forum Infectious Diseases, 7(6). https://doi.org/10.1093/OFID/OFAA198

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