The features of psycho-vegetative disorders and their role in the pathogenesis of gastroesophageal reflux disease with obesity

Abstract

Background: Gastroesophageal reflux disease (GERD) is a disease of the XXI century, affecting the population in the developed countries. There is a clear tendency to increasing of gastroesophageal reflux disease among people of young age. Aim: The aim of the study is to determine the characteristics and role of psychosomatic and vegetative state disorders in the pathogenesis of GERD with concomitant obesity. Materials and methods: 50 young patients with GERD were examined during the study. Depending on the presence or absence of concomitant obesity, two groups were formed. They underwent pH-metery, ultrasonic scanning. State of psychosomatic, vegetative statuses and quality of life we determined by the questionnaires of Beck, Spielberg, Sheehan, Wayne. Results: During the ultrasound examination we determined the esophageal opening diameter, the thickness of esophageal wall, the esophagus width in the lower one third of the esophagus differed significantly in 2 groups of patients (p<0.05). In the group of the GERD patients with concomitant obesity the sharp increase of depression level was found, comparing with both the standard and the second group (p<0.05). It wasn’t found the significant difference amount other figures of vegetative and psychosomatic statuses in 2 groups of patients (p>0.05). The patients with GERD of both groups had significantly higher level of motor-evacuation and psycho-vegetative disorders comparing with healthy people (p<0.05). Conclusion: GERD patients have pronounced motor-evacuation disorders and significantly greater manifestations of psycho-vegetative disorders which were more pronounced in gastroesophageal reflux disease patients with concomitant obesity.