A new hydrogenated azaphilone Sch 725680 from Aspergillus sp.

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Abstract

A new hydrogenated azaphilone Sch725680 (1) was isolated and identified from the culture of an Aspergillus sp. The structure elucidation of 1 was achieved based on extensive NMR spectroscopic analyses. Compound 1 showed inhibitory activity against Saccharomyces cerevisiae (PM503) and Candida albicans (C43) with MICs of 8 and 64 μg/ml, respectively. © Japan Antibiotics Research Association.

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Yang, S. W., Chan, T. M., Terracciano, J., Patel, R., Patel, M., Gullo, V., & Chu, M. (2006). A new hydrogenated azaphilone Sch 725680 from Aspergillus sp. Journal of Antibiotics, 59(11), 720–723. https://doi.org/10.1038/ja.2006.96

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