Abstract
Bovine-origin Escherichia coli isolates were tested for resistance phenotypes using a disk diffusion assay and for resistance genotypes using a DNA microarray. An isolate with gentamicin and amikacin resistance but with no corresponding genes detected yielded a 1,056-bp DNA sequence with the closest homologues for its inferred protein sequence among a family of 16S rRNA methyltransferase enzymes. These enzymes confer high-level aminoglycoside resistance and have only recently been described in Gram-negative bacteria. Copyright © 2010, American Society for Microbiology. All Rights Reserved.
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CITATION STYLE
Davis, M. A., Baker, K. N. K., Orfe, L. H., Shah, D. H., Besser, T. E., & Call, D. R. (2010). Discovery of a gene conferring multiple-aminoglycoside resistance in Escherichia coli. Antimicrobial Agents and Chemotherapy, 54(6), 2666–2669. https://doi.org/10.1128/AAC.01743-09
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