Spirometric Abnormalities in Patients with Type 2 Diabetes Mellitus

Abstract

BACKGROUND We wanted to document abnormalities on spirometry in patients with type 2 diabetes mellitus (DM) and study the determinants of these. METHODS This is a hospital based cross sectional study. Fifty-two type 2 DM patients attending the diabetic clinic of Shri B. M. Patil Medical College Vijayapur, Karnataka, were included in this study and they underwent spirometry after giving consent for the study. The absolute FEV1 and FVC were compared with the predicted ones and expressed as a percentage of the predicted values. Additional information collected were, gender, age, weight, height and the latest glycated haemoglobin. Data was presented as mean ± SD. χ2 test was used to study differences in proportions and Pearson’s coefficient was calculated for correlations. RESULTS 52 patients with type 2 DM were recruited in this study between November 2015- July 2017. Thirty were males (58%) and twenty-two (42%) were females. Forty-five patients (86%) had restrictive abnormality on PFT in our study. In seven patients, PFT reports were normal. The mean FEV1, FVC & FEV1/FVC were 75% pred, 70% pred and 117 respectively. Out of 52 patients only 7 patients were having normal PFT study while remaining 45 patients were restrictive form of abnormality on PFT which was statistically significant (p <0.05). CONCLUSIONS Spirometric abnormalities are common in Type 2 DM and is a significant determinant of the same. KEY