An advanced gastric cancer with peritoneal dissemination: Complete response achieved with FLOT combination chemotherapy

Abstract

Introduction: Although chemotherapy is the first recommended treatment of metastatic gastric cancer, a complete response is a rare event. Case: A 56-year-old male was diagnosed as gastric cancer with gastric outlet obstruction, large bowel obstruction and peritoneal dissemination. The patient underwent gastrojejunostomy bypass and ileostomy diversion, and chemotherapy with FLOT (5FU, leucovorin, oxaliplatin, docetaxel) regimen subsequently. After 6 courses of chemotherapy, a computed tomography showed disappearance of gastric mass and disseminated nodules in pelvic cavity, and no visible lesion in gastric mucosa, suggesting a complete clinical response. Conclusion: FLOT regiment in our case succeed to achieve complete clinical response.