Recent works on anti-tumor constituent from Annonaceae plants in China

Abstract

This review describes the recent works on anti-tumor constituent from family Annonaceae plants in our laboratory. About 50 new Annonaceous acetogenins, 12 new styrylpyrones and 25 new polyoxygenated cyclohexenes were isolated from 5 Uvaria species, 4 Goniothalamus species and 1 species of Annona. The structure and stereochemistry of new compounds were determined by means of spectral analysis and chemical reactions as well as X-ray diffractions in few cases. Preliminary bioassay tests showed most of the new isolates exhibit significant anti-tumor activities. © 1999 IUPAC.