The versatility of liver X receptors in T cell homeostasis: Location, location, location!

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Abstract

Nuclear receptors control the transcriptional program of target cells and thereby their phenotype and activities. Two complementary studies by Micheals et al. (https://doi.org/10.1084/jem.20201311) and Chan et al. (https://doi.org/10.1084/jem. 20200318) published in JEM uncover the cell type-specific expression and role of the nuclear receptors liver X receptors in the regulation of T cell homeostasis and function.

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Phan, T. S., & Brunner, T. (2021, April 5). The versatility of liver X receptors in T cell homeostasis: Location, location, location! Journal of Experimental Medicine. Rockefeller University Press. https://doi.org/10.1084/JEM.20202318

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