S100A12: A noninvasive marker of inflammation in inflammatory bowel disease

Abstract

Inflammatory bowel diseases are incurable conditions that feature gut inflammation. Standard markers have inadequate sensitivity and specificity. S100A12 is a new fecal marker that has promise as a non-invasive indicator of gut inflammation. This article reviews recent studies focusing on S100A12 and highlights the current and potential roles of this biomarker. © 2012 The Authors. Journal of Digestive Diseases © 2012 Chinese Medical Association Shanghai Branch, Chinese Society of Gastroenterology, Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine and Wiley Publishing Asia Pty Ltd.