Abstract
We report a facile intracellular manipulation of fluorescent magnetic Fe3O4-CdSe nanoparticles using magnetic force. The growth of CdSe quantum dots on Fe3O4 nanoparticles produces Fe3O4-CdSe nanoparticles with two distinct properties, fluorescence and superparamagnetism. After nonspecific surface modification using glutathione (GSH), the hydrophilic Fe3O4-CdSe@GSH nanoparticles can be easily uptaken by an HEK293T cell line. Confocal images indicate that the uptaken nanoparticles can be manipulated using a small magnet. The successful intracellular manipulation of magnetic nanoparticles may offer a new strategy for studying polarized cells. Copyright © 2008 American Chemical Society.
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CITATION STYLE
Gao, J., Zhang, W., Huang, P., Zhang, B., Zhang, X., & Xu, B. (2008). Intracellular spatial control of fluorescent magnetic nanoparticles. Journal of the American Chemical Society, 130(12), 3710–3711. https://doi.org/10.1021/ja7103125
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