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β2-Chimaerin in cancer signaling: Connecting cell adhesion and MAP kinase activation

Cell Cycle
DOI: 10.4161/cc.6.20.4786
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Abstract

The chimaerins are Rac GTPase-activating proteins that bind diacylglycerol. Emerging evidence implicates β2-chimaerin in tumor progression. Here, we discuss our recent work in Drosophila melanogaster in the context of previous studies performed in human cancer cell lines that together lend new mechanistic insight into the role of chimaerins in cancer. ©2007 Landes Bioscience.

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Bruinsma, S. P., & Baranski, T. J. (2007, October 15). β2-Chimaerin in cancer signaling: Connecting cell adhesion and MAP kinase activation. Cell Cycle. Taylor and Francis Inc. https://doi.org/10.4161/cc.6.20.4786

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