Characteristics and Longitudinal Patterns of Erectile Dysfunction Drug Use Among Men Who Have Sex with Men in the U.S.

Abstract

We investigated the longitudinal relationship between erectile dysfunction (ED) drug use with behavioral factors, including substance use and sexual activities in men who have sex with men from the Multicenter AIDS Cohort Study during 1998–2016 (n = 1636). We used a bivariate random-intercept model to evaluate ED drug use along with other behavioral factors to assess relationships between the two outcomes over time on a population level and also at the individual level. Average ED drug use among men who have sex with men (MSM) with HIV was positively correlated with average use of marijuana (r =.19), poppers (r =.27), and stimulants (r =.25). In this group, testosterone use (r =.32), multiple partners (r =.41), insertive anal intercourse with condom (r =.40), and insertive anal intercourse without condom (r =.43) all showed moderate correlations over time with average ED use (p