68Ga-FAPi: Pathways and Diagnosis in Cardiac Imaging

Abstract

Purpose of Review: Myocardial fibrosis is a response to myocardial injury and plays a pivotal role in ventricular remodeling. Different patterns of fibrosis are associated with different disease states, but the presence and amount of fibrosis provide a different impact on prognosis. Recent Findings: In the latest years, fibroblast activation protein inhibitor (FAPi) positron emission tomography (PET) gain interest for its potential in detecting myocardial fibrosis, in differentiating between active and chronic disease, and in the assessment of disease progression and response to treatment. Summary: We aim to highlight the most relevant current applications of FAPi PET/CT in cardiovascular imaging, focusing on its applications, advantages, limitations, and to underline future clinical perspective.