Diagnostic and prognostic values of anti-helicobacter pylori antibody combined with serum CA724, CA19-9, and CEA for young patients with early gastric cancer

Abstract

Background: To investigate the value of anti-helicobacter pylori (Hp) antibody, serum carbohydrate antigen (CA)-724, CA19-9, and carcinoembryonic antigen (CEA) in the diagnosis and prognosis evaluation of young patients with early gastric cancer. Methods: A total of 200 young patients with gastric cancer from April 2014 to December 2015 were enrolled. A total of 206 patients with gastritis and 204 healthy subjects were also selected. Gastric cancer patients were followed up for 3 years, and the number of recurrences, metastasis, and death was recorded. Results: The positive rate of anti-Hp antibody, CA724, CA19-9, and CEA in young patients with early gastric cancer were significantly higher than those in gastritis and healthy subjects (P