Gonococcal OMV-delivered PorB induces epithelial cell mitophagy

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Abstract

Neisseria gonorrhoeae secretes outer membrane vesicles (OMV) during colonization of epithelial cells. Here, the authors demonstrate that gonococcal OMVs induce epithelial cell mitophagy by a PorB-dependent mechanism to enhance intracellular survival.

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Gao, S., Gao, L., Yuan, D., Lin, X., & van der Veen, S. (2024). Gonococcal OMV-delivered PorB induces epithelial cell mitophagy. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-45961-1

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