Polymorphisms in CSN3, CSN2 and LGB genes and their relation to milk production in dairy cattle in the Czech Republic

Abstract

The principal objective of this study was to perform genotyping of the CSN3, CSN2 and LGB genes in selected dairy cattle breeds in the Czech Republic, to determine genotype and allele frequencies and to perform an associative analysis on milk yield in kg, the percentage of fat and protein content, and fat and protein production in kg. The AA was the most frequent genotype for CSN3 with a frequency of 0.474 and the A allele (0.694). The BB genotype (0.814) and the B allele (0.895) predominated in CSN2 gene. Other genotyping was performed for the A1 and A2 alleles, the most frequent were the A2A2 genotype (0.475) and the A2 allele (0.680). The heterozygous AB genotype with a frequency of 0.900 was the most frequent in the LGB gene. A statistically significant higher protein content was found in the AB genotype in comparison to the BB in gene for CSN2. In the remaining cases, the effect of CSN3, CSN2 and LGB polymorphic variations on the milk production indicators was not statistically significant.