Antimicrobial and Anti-inflammatory Effects of Two Different Marine Red Algae Species Collected from Quseir, the Red Sea, Egypt

Abstract

This study aimed to analyze the bioactivities of two different species of marine red algae crude extracts; Acanthophora spicifera (M.Vahl) Borgese and Digenea simplex (Wulfen) C.Agardh. Place and Duration of Study: Sample: Quseir city, Red Sea, Egypt at (April, 2015), extraction and biological study; pharmacognosy department, summer 2015, Kasr El-Eini Teaching Hospitals, Cairo University, Egypt. Methodology: The crude extract screened against some human pathogenic bacteria including ten Gram positive, ten Gram negative strains and ten unicellular and filamentous fungi. The antimicrobial activity was done through the agar well diffusion method. The anti-inflammatory effect of the crude extract on inflammed liver cells was evaluated by measuring SOD, MDA, catalase, GSH, Il-6 and TNF-alpha in the serum of treated Wister albino rats compared to positive and negative control groups.