Synthesis, characterization and x-ray crystal structure of 3-Methyl-4-oxo-7-phenyl-4,7-dihydrothieno[2,3-b]pyridine-2-carboxyxlic acid ethyl ester

Abstract

Synthesis of 3-methyl-4-oxo-7-phenyl-4,7-dihydrothieno[2,3-b]pyridine-2-carboxylic acid ethyl ester (3) is described. The structure of the title compound 3 is confirmed by NMR, FT-IR, MS, CHN microanalysis, and X-ray crystallography. Compound 3 is a useful, functionalized pyrido thiophene derivative that can be transformed to novel heteroaromatics of potential pharmacological activities.