Potensi Ekstrak Moringa Oleifera Untuk Mengatasi Gastroenteritis Bakteri

  • Kusbijantoro Y
  • Naufizdihar N
  • Adji A
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Abstract

ABSTRACT   Bacterial gastroenteritis is a disease in the tropics in the form of inflammation of the stomach and intestines due to several bacteria, such as Salmonella,Campylobacter, Shigella, E. coli, Vibrio, Yersinia, and Listeria with symptoms of diarrhoea without or with vomiting, and frequent fever. Gastroenteritis is a global disease with the highest prevalence in the agricultural community, especially farmers and fishermen. This reasearch to determine the potential of leaf and seed extract Moringa oleifera as an alternative therapy for bacterial gastroenteritis. Methods: The journal writing method uses a literature review approach derived from the analysis and synthesis of various related references. The author selects journals full text and books published in the last ten years maximum through several databases, namely PubMed, Google Scholar, Science Direct, and Cochrane with the keywords: diarrhoea, gastroenteritis, and Moringa oleifera. Results: seed and leaf extract Moringa oleifera played a role in preventing some of the effects of the pathogenesis of diarrhoea due to bacterial infection. Methanol, N-hexane, ethyl acetate, flavonoids, phenols, saponins, alkaloids, tannins, and steroids from seed and leaf extract Moringa oleifera have antibacterial effects. The content of quercetin has an anti-inflammatory effect. The content of tannins, flavonoids, and alkaloids has antidiarrheal activity. The content of ethanol and tannins has an antiulcer effect. This potential can help cure patients with bacterial gastroenteritis.ABSTRAK   Gastroenteritis bakteri adalah salah satu penyakit di daerah tropis berupa peradangan lambung dan usus akibat beberapa bakteri, seperti Salmonella, Campylobacter, Shigella, E. coli, Vibrio, Yersinia, dan Listeria dengan gejala diare tanpa maupun disertai muntah, dan sering demam. Gastroenteritis menjadi penyakit global dengan prevalensi tertinggi pada komunitas agrikultur terutama petani dan nelayan. Penelitian ini bertujuan untuk mengetahui potensi ekstrak daun dan biji Moringa oleifera sebagai alternatif terapi gastroenteritis bakteri. Metode penulisan jurnal menggunakan pendekatan tinjauan pustaka yang berasal dari analisis dan sintesis berbagai referensi terkait. Penulis memilih jurnal full text dan buku tahun terbit maksimal sepuluh tahun terakhir melalui beberapa database, yaitu PubMed, Google Scholar, Science Direct, dan Cochrane dengan kata kunci: diare, gastroenteritis, dan Moringa oleifera. Ekstrak biji dan daun Moringa oleifera berperan dalam mencegah beberapa efek dari patogenesis diare akibat infeksi bakteri. Metanol, N-hexane, etil asetat, flavonoid, fenol, saponin, alkaloid, tanin, dan steroid dari ekstrak biji dan daun Moringa oleifera memiliki efek antibakteri. Kandungan quercetin memiliki efek antiinflamasi. Kandungan tanin, flavonoid, dan alkaloid memiliki aktivitas antidiare. Kandungan etanol dan tanin memiliki efek antiulkus. Potensi tersebut dapat membantu penyembuhan penderita gastroenteritis bakteri.

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CITATION STYLE

APA

Kusbijantoro, Y. B., Naufizdihar, N. A., & Adji, A. S. (2022). Potensi Ekstrak Moringa Oleifera Untuk Mengatasi Gastroenteritis Bakteri. JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia, 9(3), 54–63. https://doi.org/10.53366/jimki.v9i3.460

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