Detection and comparison of microRNAs in the caprine mammary gland tissues of colostrum and common milk stages

Abstract

Background: MicroRNAs (miRNAs) have a great influence on various physiological functions. A lot of high-throughput sequencing (HTS) research on miRNAs has been executed in the caprine mammary gland at different lactation periods (common milk lactation and dry period), but little is known about differentially expressed miRNAs in the caprine mammary gland of colostrum and peak lactation periods. Result: This study identified 131 differentially expressed miRNAs (P<0.05 and log2 colostrum normalized expression (NE)/peak lactation NE>1 or log2 colostrum NE/peak lactation NE <0.05 and log2 colostrum NE/peak lactation NE>1 or log2 colostrum NE/peak lactation NE