Declining hospitalisation and surgical intervention rates in patients with Crohn's disease: a population-based cohort

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Abstract

Background: Lifetime risk of surgery in patients with Crohn's disease remains high. Aim: To assess population-level markers of Crohn's disease (CD) in the era of biological therapy. Methods: Population-based cohort study using administrative data from Ontario, Canada including 45 235 prevalent patients in the Ontario Crohn's and Colitis Cohort (OCCC) from 1 April 2003 to 31 March 2014. Results: CD-related hospitalisations declined 32.4% from 2003 to 2014 from 154/1000 (95% confidence interval (CI) [150, 159]) patients to 104/1000 (95% CI [101, 107]) (P

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Rahman, A., Jairath, V., Feagan, B. G., Khanna, R., Shariff, S. Z., Allen, B. N., … Benchimol, E. (2019). Declining hospitalisation and surgical intervention rates in patients with Crohn’s disease: a population-based cohort. Alimentary Pharmacology and Therapeutics, 50(10), 1086–1093. https://doi.org/10.1111/apt.15511

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