Transition metal oxide based non-enzymatic electrochemical sensors: An arising approach for the meticulous detection of neurotransmitter biomarkers

Abstract

Diagnosis of brain disorders is an extremely confronting task for the medical community and hence, the recognition and detection of pertinent biomarkers for neurological disorders is a crucial phase. Electrochemical techniques with transition metal oxide (TMOs) modified electrodes have emerged as a promising technique for the detection of neurotransmitters, which act as potent biomarkers. This review has tried to sum up the recent advancements made in the TMOs modified non-enzymatic electrochemical detection of important neurotransmitters in the last two decades. A comprehensive description of these neurotransmitters along with their biochemistry and impact on the human body is also provided. A short description of the future perspectives of the electrochemical detection of neurotransmitters is given highlighting the wearable sensors for the in vivo detection.