Advantages of ramipril/amlodipin fixed combination therapy. When should we use it?

Abstract

Hypertension is one of the most frequent chronic disease in Hungary and one of the most important cardiovascular risk factor. Treatment of blood pressure to target value lowers significantly the risk of coronary artery disease, stroke and chronic renal disease as well as it decreases mortality. Blood pressure control has a great importance in high risk patients. In addition to life style changes, drug treatment plays an essential role in the management of hypertensive patients. The complexity of drug regimen, characteristics of drug class, age and gender are all exert impacts on patient adherence. Antihypertensive drugs should preferably have metabolically neutral properties and cardiovascular protective effects. Ramipril/amlodipine fixed combination meets these criteria and adherence of patients is favorable. Orv. Hetil., 154 (42), 1658–1664.