Subsystem organ function during coronary surgery

Abstract

Conventional coronary artery bypass grafting (CABG) carries a mortality rate of 1% to 2% in elective patients. However, despite advances in perfusion, anaesthetic, and surgical techniques cardiopulmonary bypass (CPB) is still associated with subsystem dysfunction. Off-pump coronary artery bypass grafting (OPCAB) has recently gained popularity as a potentially more physiological method to maintain the functional integrity of major organ systems. The review of observational reports, casematched studies and prospective randomized trials seems to suggest that OPCAB surgery reduces post-operative subsystem organ dysfunction when compared with conventional coronar revascularisation.