Model-based determination of the influence of textile fabric on bioassay analysis and the effectiveness of a textile slow-release system of DEET in mosquito control

Abstract

BACKGROUND: Determining the effectiveness of a product in repelling mosquitoes or other flying insects is a difficult task. One approach is to use a bioassay with textile fabric. We investigated the role of the textile substrate in a bioassay with a numerical model, and compared the outcome with known results for DEET. The model was then used to determine the effectiveness of textile slow-release formulations based on coatings, and results were compared with those of a field study in the Cameroon. Slow-release formulations are difficult to evaluate with standard tests, as the compound needs a build-up time not present in these tests. RESULTS: We found excellent correspondence between the model and the known DEET results without matching parameters. Slow-release approaches are deemed possible but have several drawbacks. Modelling can help in identifying optimal use conditions. The field test with a slow-release system performed better than anticipated by the model, with initially more than 90% repellency. DEET-coated textile was considered not to be marketable, however. CONCLUSION: We advise that bioassays characterise in more detail the type of textile fabric used so as to allow conclusions to be drawn by textile modelling. As regards coated-textile slow-release systems, more research is needed. We nevertheless advise usage mainly at entry points, e.g. as scrims.