Study on pH effect in process of an entero-gastric fiber-optic sensor design

Abstract

The pH effect on design of a fiber optic sensor newly developed for monitoring entero-gastric reflux is investigated. The research has been carried out by utilizing the sensor to measure characteristic absorption of bilirubin standard solution (used as a calibrator) at different pH values from about 1 to 8. The results show explicitly that the estimation error according to the calibration curves with pH <7 is significantly lower than that at alkaline pH values. Compared with the in vitro experimental data, the optimum pH range for entero-gastric reflux analysis is proposed to be between 5-6. The possible reasons for estimation error of the fiber optic sensor are given in detail. © 2002 by MDPI.