Clinical Presentation and Factors Associated with Diabetic Ketoacidosis at the Onset of Type-1 Diabetes Mellitus in Children and Adolescent at Muhimbili National Hospital, Tanzania: A Cross Section Study

Abstract

Background: The incidence and clinical presentation of Type 1 diabetes mellitus (T1DM) varies markedly among countries with a worldwide trend of affected children under -5 years of age. The classical triad of polydipsia, polyuria and weight loss is the most common presentation. Similarly, the frequency of Diabetic Ketoacidosis (DKA) at the onset of T1DM is persistently high in Africa affecting more than two thirds of diabetic children.