Liver injury following small intestinal ischemia reperfusion in rats is attenuated by Pistacia lentiscus oil: antioxidant and anti-inflammatory effects

Abstract

Context: Intestinal ischemia-reperfusion (IIR) not only leads to severe intestine damage but also induced subsequent destruction of remote organs. Objective: We investigated the protective effect of Pistascia lentiscus L. (Anacardiaceae) oil on IIR. Materials and methods: Wistar rats were divided into three groups: sham, intestinal IR and P. lentiscus pretreatment (n = 18 each). In the pretreatment group, oil was administered 1 h before induction of warm ischemia. Results: IIR led to severe liver damage manifested as a significant (p