Revisit to (Z)-civetone synthesis

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Abstract

The synthesis of (Z)-civetone (1) is described starting from oleic acid (5 ) via a series of reactions, intermolecular olefin self-metathesis, bromination/dehydrobromination into acetylene, semi-hydrogenation and intramolecular Dieckmann macrocyclization.

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Hagiwara, H., Adachi, T., Nakamura, T., Hoshib, T., & Suzukib, T. (2012). Revisit to (Z)-civetone synthesis. Natural Product Communications, 7(7), 913–915. https://doi.org/10.1177/1934578x1200700728

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