Inhibition of CD40L with Frexalimab in Multiple Sclerosis

  • Vermersch P
  • Granziera C
  • Mao-Draayer Y
  • et al.
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Abstract

Abstract Background The CD40–CD40L costimulatory pathway regulates adaptive and innate immune responses and has been implicated in the pathogenesis of multiple sclerosis. Frexalimab is a second-gen...

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Vermersch, P., Granziera, C., Mao-Draayer, Y., Cutter, G., Kalbus, O., Staikov, I., … Giovannoni, G. (2024). Inhibition of CD40L with Frexalimab in Multiple Sclerosis. New England Journal of Medicine, 390(7), 589–600. https://doi.org/10.1056/nejmoa2309439

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