Patient maintained propofol sedation for dental surgery

Abstract

Aim: This study evaluated a system for patients to operate a target-controlled infusion (TCI) of propofol for sedation. Participants: 50 healthy adults, undergoing minor oral surgical procedures under local anaesthesia. Methods: Following instructions, patients were allowed to control their own sedation to comfortably undergo surgery. Outcome Measures: Operating conditions, degree of sedation, vital signs and patients' assessment of the technique. Results: Operating conditions were described as good in 47 patients and fair in 3. Optimal sedation was provided at a median target blood concentration of 2 mcg/ml (range1-3mcg/ml). 30 were sedated moderately, 16 deeply and 4 mildly. None were oversedated. The vital signs were stable in all patients. 30% of patients had injection pain and 28% became talkative. Patient satisfaction was high with 86% feeling adequately relaxed and 92% willing to use it again. 14 patients had complete and 22 had partial amnesia for the procedure. Conclusions: This technique combines the benefits of target-controlled infusion with patient-controlled feedback and produces safe dental sedation.