Proton pump inhibitors in veterinary medicine

Abstract

Inhibition of gastric acid secretion is necessary to treat many gastrointestinal diseases. Proton Pump Inhibitors (PPIs) are very effective drugs, used for gastric acid inhibition and therapy of important erosive and non-erosive gastrointestinal disorders in animals as well as humans. In this review, general properties of PPIs, their mode of action, pharmacokinetics, efficacy, adverse effects, drug interactions and clinical and alternative uses in veterinary medicine were evaluated.