Counting intraepithelial lymphocytes. Immunohistochemistry and flow cytometer are necessary new steps in the diagnosis of celiac disease

Abstract

The simple quantitation of intraepithelial lymphocytes per 100 epithelial cells in small bowel has been a valuable addition to the study of the histopathology of celiac disease. However new technology is necessary to increase the accuracy and significance of the subtypes of intraepithelial lymphocytes in the differential diagnosis and the evaluation of gluten related disorders.