Novel macrocyclic derivatives of diterpenoid isosteviol

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Abstract

A series of novel macrocycles was synthesized on the basis of diterpenoid isosteviol (16-oxo-ent-beyeran-19-oic acid) obtained by acid hydrolysis of the glycosides of the plant Stevia rebaudiana. The macrocycles contain two or four isosteviol moieties connected by diester linkers of various length. Molecular structure of several macrocycles was determined by single crystal X-ray diffraction. © ISUCT Publishing.

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Andreeva, O. V., Strobykina, I. Y., Kataeva, O. N., Dobrynin, A. B., Babaev, V. M., Rizvanov, I. K., … Kataev, V. E. (2013). Novel macrocyclic derivatives of diterpenoid isosteviol. Macroheterocycles, 6(4), 315–322. https://doi.org/10.6060/mhc131056k

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