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Impact of alginate overproduction on attachment and biofilm architecture of a supermucoid Pseudomonas aeruginosa strain

Applied and Environmental Microbiology (2009) 75(18) 6022-6025
DOI: 10.1128/AEM.01078-09
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Abstract

The supermucoid Pseudomonas aeruginosa strain PDO300Δalg8(pBBR1MCS-5: alg8) showed strongly impaired attachment compared with the respective mucoid or nonmucoid strains and formed a thicker biofilm with large extended mushroom-like microcolonies. Alginate lyase treatment dissolved microcolonies. The data suggested that alginate overproduction impairs attachment but plays a structural role in microcolony formation. Copyright © 2009, American Society for Microbiology. All Rights Reserved.

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Hay, I. D., Gatland, K., Campisano, A., Jordens, J. Z., & Rehm, B. H. A. (2009). Impact of alginate overproduction on attachment and biofilm architecture of a supermucoid Pseudomonas aeruginosa strain. Applied and Environmental Microbiology, 75(18), 6022–6025. https://doi.org/10.1128/AEM.01078-09

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