Polyurethane Nanocapsules Incorporating Epigallocatechin Gallate, A Green Tea Extract

Abstract

Explosions cause 79% of combat-related injuries, often leading to traumatic brain injury (TBI) and hemorrhage. Epigallocatechin gallate (EGCG), a green tea polyphenol, aids neuroprotection and wound healing. In this work, we sought to investigate the fabrication and characterization of polyurethane nanocapsules encapsulating EGCG, demonstrating controlled, on-demand release, and highlighting their potential for targeted therapeutic delivery in trauma care.