Advancements in Early Detection and Targeted Therapies for Breast Cancer; A Comprehensive Analysis

Abstract

Background: Breast cancer is a leading cause of morbidity and mortality among women worldwide. Early detection and targeted therapies have significantly improved outcomes, yet challenges remain in optimizing these approaches, especially in resource-limited settings like Rajshahi Medical College Hospital. Objective: This study aims to evaluate the advancements in early detection and targeted therapies for breast cancer, assessing their effectiveness and impact on patient outcomes at Rajshahi Medical College Hospital. Method: A retrospective analysis was conducted on 216 breast cancer patients treated at Rajshahi Medical College Hospital from June 2021 to June 2022. Data were collected on demographic characteristics, diagnostic methods, treatment regimens, and outcomes. The study focused on the use of advanced imaging techniques, liquid biopsies, and targeted therapies, including hormone receptor modulators and HER2-targeted treatments. Statistical analysis was performed to evaluate the efficacy of these interventions. Result: A total 216 patients, 68% were diagnosed at early stages (Stage I or II) due to advanced imaging and diagnostic tools. Targeted therapies were administered to 57% of the patients, with a significant reduction in disease progression observed in 74% of those treated with HER2-targeted therapies. Overall, the one-year survival rate was 89%, with a notable improvement in quality of life. Conclusions: The integration of advanced diagnostic tools and targeted therapies has substantially improved early detection rates and patient outcomes at Rajshahi Medical College Hospital. These findings underscore the importance of continued investment in modern technologies for breast cancer management in resource-limited settings.