Oral mucosa- Gate for covid-19 infection and correlation with chemical structures of the biocides

Abstract

The oral mucosa is a mirror of the state of health for the whole organism, representing a natural barrier to infection, an entry gate for a large number of pathogens, a site for microbial multiplication and for initiating disease- specific pathological processes, expressed by lesions, signs and symptoms characteristic for diagnosis. The new global threat to public health, COVID-19 infection can be customized within the oral pathology. The new SARS-CoV-2 coronavirus is characterized by high contagiousness, airborne transmission, directly through inhaled drops or, indirectly, through the use of contaminated objects. The survival of the virus on surfaces, depending on their structure, varies from 4 hours to 9 days. The initiation of infection is possible through the binding of viruses in site of host cells, due to receptor affinity and an angiotensin converting enzyme (ACE2), distributed in the epithelium, alveoli, ascular endothelium, lung pneumocytes and macrophage. The severity of the infection varies from asymptomatic forms to severe complications, with high motility. In the absence of a treatment or vaccine with proven efficacy, to be approved for use in practice, prevention is limited to respecting hygiene and social spacing, proper use of protective equipment and limiting services and procedures at risk of dispersing aerosols and saliva.