A new model of bilateral hemispheric ischemia in the rat — three vessel occlusion model

Abstract

A new model of bilateral hemispheric ischemia was created in the rat by occluding the common carotid arteries and the basilar artery; this resulted in consistent and severe impairment of the cerebral blood flow. The procedure for producing this model is described, and the results of EEG and autoradiography obtained by this model are compared to those obtained by the four-vessel occlusion model. © 1985 American Heart Association, Inc.