Determination of in vitro antioxidant activity of the leaves extracts of ehretia pubescens

Abstract

The foods from plants were known to ensure against degenerative diseases and maturing because of their antioxidant activity credited to their high polyphenolic content. Information on antioxidant activity of Indian medicinal plant is abundant. To the best of our knowledge, biological properties have not been accounted in the literature for this species of Ehretia. As a point, this is the first results to assess the anti-oxidant activity of the plant Ehre-tia pubescens Benth which belongs to the family Ehretiaceae. The antioxi-dant activity of Methanol, Hexane, Ethyl acetate and Aqueous extracts of E. Pubescens was determined using the DPPH free radical scavenging activity, ABTS radical scavenging activity and reducing power assay. The DPPH scavenging activity showed higher activity observed in methanolic extract (63%) of E.pubescens than ethylacetate (54%), hexane (44%) and aqueous (30%). Similarly the ABTS assay showed highest inhibition in methanolic extract (58%) than ethylacetate (43%), hexane (38%) and aqueous (32%) extracts. The reducing power assay of different extracts was increased in methanolic extract (54%) than ethylacetate (40%), hexane (34%) and aqueous (28%) extracts. Overall, the methanolic and ethyl acetate extract had higher antioxi-dant properties than other extract. However, in this study, Ehretia Pubescens Benth extracts exhibit great potential for antioxidant activity and may be useful for their nutritional and medicinal functions.