Intramolecular Barbier reaction in water: Cyclopentane and cyclohexane ring closure

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Abstract

Zinc or indium promoted intramolecular Barbier reactions of aldehydes containing a suitably positioned allylic or propargylic halide unit afford unsaturated cyclic alcohols in moderate yields.

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Ivković, A., Matović, R., & Saičić, R. N. (2002). Intramolecular Barbier reaction in water: Cyclopentane and cyclohexane ring closure. Journal of the Serbian Chemical Society, 67(3), 141–148. https://doi.org/10.2298/JSC0203141I

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