Phosphine-Catalyzed Dearomative [3 + 2] Cycloaddition of Benzoxazoles with a Cyclopropenone

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Abstract

The triphenylphosphine-catalyzed dearomative [3 + 2] cycloaddition of benzoxazoles with 1,2-diphenylcyclopropenone is herein described. The reaction scope, mechanism, and possible future applications of this rare organocatalyzed cycloaddition are herein discussed.

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Wang, X., Yu, C., Atodiresei, I. L., & Patureau, F. W. (2022). Phosphine-Catalyzed Dearomative [3 + 2] Cycloaddition of Benzoxazoles with a Cyclopropenone. Organic Letters, 24(5), 1127–1131. https://doi.org/10.1021/acs.orglett.1c04045

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