Contaminated vaccine is one unexpected and potential origin of virus infection. In order to investigate the most likely cause of disease in a broiler breeder company of Shandong Province, all 17 batches of live-virus vaccines used in the affected flocks and 478 tissue samples were tested by dot-blot hybridization, nested PCR, and IFA. The results suggested the outbreak of disease was most probably due to the vaccination of REV-contaminated MD-CVI988/Rispens vaccines and ND-LaSota+IB-H120 vaccines. Furthermore, the REV was probably transmitted to the commercial chickens through congenital transmission. © 2012 Wei et al.
CITATION STYLE
Wei, K., Sun, Z., Zhu, S., Guo, W., Sheng, P., Wang, Z., … Zhu, R. (2012). Probable congenital transmission of reticuloendotheliosis virus caused by vaccination with contaminated vaccines. PLoS ONE, 7(8). https://doi.org/10.1371/journal.pone.0043422
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