Comparison of Outcomes between Vaccinated versus Non-Vaccinated Covid-19 Patients

Abstract

Objective: To compare the outcomes in term of hospital stay and mortality between vaccinated and nonvaccinated covid-19 patients. Study Design: Prospective/Observational Place and Duration: The study was conducted at Medicine department of Fauji Foundation Hospital Rawalpindi and Pak International Medical College Hayatabad Peshawar for six months duration from December 2020 to May 2021. Methodology: One hundred ten patients of either gender with covid-19 disease were enrolled. All the patients were confirmed with RT PCR. Patients were randomly divided in to two groups. Group I (vaccinated) comprised of 45 patients and group II (non-vaccinated) comprised of 65 patients. Severity of disease, hospital stay and mortality were compared between both groups. Data was analyzed by SPSS 24.0. Results: There were 74 (67.27%) males while 36 (32.73%) patients were females. Mean age of patients was 50.54±12.76 years. Mean BMI was 26.23±2.44 kg/m2. 10 (22.22%) patients in vaccinated group and 40 (61.54%) in nonvaccinated group had severe covid-19 disease, a significant difference was observed regarding severity of disease between both groups with p-value <0.05. Mortality rate and hospital stay were also high in nonvaccinated patients as compared to vaccinated (p-value <0.05). Conclusion: It is concluded that non-vaccinated patients of covid-19 had prolonged hospital stay and high rate of severity of disease and mortality as compared to vaccinated patients. Keywords: Covid-19, Vaccination, Severity, Hospital Stay, Mortality